Developed by the National Institutes of Health, the Centers for Disease Control and Prevention, and the HIV Medicine Association of the Infectious Diseases Society of America Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV—A Working Group of the NIH Office of AIDS Research Advisory Council (OARAC)
This clear language document was designed to remove language barriers about common phrases, terms, and diseases that are discussed within BCCDC projects and applicable to data requests that might be considered by community.
This glossary provides lay language definitions for frequently used health research terms.
Adaptive trial design has been proposed as a means to increase the efficiency of randomized clinical trials, potentially benefiting trial participants and future patients while reducing costs and enhancing the likelihood of finding a true benefit, if one exists, of the therapy being studied.
The objective of the study was to outline key considerations for general clinical readers when critically evaluating publications on platform trials and for researchers when designing these types of clinical trials.
In this review, using a series of examples derived from equivalence and non-inferiority/superiority RCTs, we describe the main differences and methodological aspects among these three different types of RCTs
This paper is a practical guide to the essentials of statistical analysis and reporting of randomized clinical trials, include statistical controversies in reporting and interpretation, the fundamentals of trial design, and statistical challenges in the design and monitoring.
Some innovations spread fast. How do you speed the ones that don’t?