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PLOS Medicine
The need for implementation science in health is now broadly recognized, and a working understanding of the qualities that make an implementation study “good” is needed more than ever before.
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JAMA
Recommendations are provided for a minimum set of items that should be addressed and included in SAPs for clinical trials. Trial registration, protocols, and statistical analysis plans are critically important in ensuring appropriate reporting of clinical trials.
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NEJM
Adaptive trial design has been proposed as a means to increase the efficiency of randomized clinical trials, potentially benefiting trial participants and future patients while reducing costs and enhancing the likelihood of finding a true benefit, if one exists, of the therapy being studied.
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J Clin Epidemiol
The objective of the study was to outline key considerations for general clinical readers when critically evaluating publications on platform trials and for researchers when designing these types of clinical trials.
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Intern Emerg Med
In this review, using a series of examples derived from equivalence and non-inferiority/superiority RCTs, we describe the main differences and methodological aspects among these three different types of RCTs
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PHAC
The Public Health Agency of Canada’s integrated bio-behavioural surveillance system—Tracks surveys—assesses the burden of HIV, hepatitis C and associated risks in key populations in Canada
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PHAC
Summary of the provincial and territorial coverage of antiretroviral therapy in Canada. Data was collected from secondary data sources between September and December 2022