Resource Library
Resources, tools, and learning opportunities from the CTN+, our collaborators, and others.
Activating Knowledge Across Our Network
Part of the CTN+ Community-Centred Knowledge Mobilization Hub, our Resource Library is a place to share documents, videos, and training resources about HIV and STBBI research, care, and related topics.
If you have ideas about what else should be included in the Library, please reach out to info@ctnplus.ca.
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J Am Coll Cardiol
This paper is a practical guide to the essentials of statistical analysis and reporting of randomized clinical trials, include statistical controversies in reporting and interpretation, the fundamentals of trial design, and statistical challenges in the design and monitoring.
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Intern Emerg Med
In this review, using a series of examples derived from equivalence and non-inferiority/superiority RCTs, we describe the main differences and methodological aspects among these three different types of RCTs
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J Clin Epidemiol
The objective of the study was to outline key considerations for general clinical readers when critically evaluating publications on platform trials and for researchers when designing these types of clinical trials.
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NEJM
Adaptive trial design has been proposed as a means to increase the efficiency of randomized clinical trials, potentially benefiting trial participants and future patients while reducing costs and enhancing the likelihood of finding a true benefit, if one exists, of the therapy being studied.
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JAMA
Recommendations are provided for a minimum set of items that should be addressed and included in SAPs for clinical trials. Trial registration, protocols, and statistical analysis plans are critically important in ensuring appropriate reporting of clinical trials.
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Trials
Findings from pragmatic trials may be used in KT to provide patients, healthcare providers and policymakers with information to optimize decisions based on how a given strategy or intervention performs under the real world conditions. However, pragmatic trials have been criticized for a number of problems.
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CATIE
This webinar provides an overview of mpox epidemiology and community-based responses, including key lessons, challenges and successes, and features Prevention & Testing co-lead Dr. Darrell Tan and Cure & Immunotherapies community co-lead Devan Nambiar
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HIV.gov
At AIDS 2024, BC/Yukon Regional Co-Lead Dr. Troy Grennan was interviewed about CTN 329, a randomized trial of doxycycline for the prevention of STIs