Studies

The CTN+ supports clinical trials to find new ways to prevent, treat and manage HIV and other STBBIs, prioritizing a community-based approach of the highest scientific and ethical standards.

Completed

Prevention & Testing

CTN 284: WelTel Retain

Promoting Engagement in Pre-ART HIV Care Through SMS Patient retention in care (continuing to see their medical professional) and adherence to treatment (following the treatment program) leads to better health outcomes for patients and is important to the success of HIV care programs. Unfortunately, many patients do not consistently remain in care. Furthermore, low-income settings…

Ongoing

Treatment & Management

CTN 292A: Screening for high-grade anal dysplasia in HIV+ MSM

Development and validation of an anal cancer screening algorithm in HIV-positive men who have sex with men (MSM) – part of HPV-SAVE study.

Completed

Prevention & Testing

CTNPT 013: Sexual health and HIV-risk management in MSM

The impact of in-clinic follow-up with a sexologist on the sexual health of HIV-serodiscordant MSM couples

Terminated

Treatment & Management

CTNPT 019: Improving outcomes with Metformin

Can metformin prevent the progression of liver fibrosis in HCV-HIV co-infected and HCV mono-infected patients with insulin resistance?

Terminated

Cure & Immunotherapies

CTNPT 020: Therapeutic HIV vaccine with early HAART treatment initiation

A pilot randomized, open label study to evaluate the effect of a therapeutic HIV vaccine consisting of PENNVAX®-GP (gag, pol, env) and INO-9012 DNA vaccine delivered via electroporation on reducing HIV viral reservoirs in infected individuals, who initiated therapy during the acute/early phase of infection

Terminated

Cure & Immunotherapies

CTNPT 022A: PROOV IT I

Probiotic Visbiome for Inflammation and Translocation in HIV (PROOV IT I)

Reporting

Cure & Immunotherapies

CTNPT 022B: PROOV IT II

Probiotic supplements for gut immune health (PROOV IT II)

Reporting

Treatment & Management

CTNPT 024: Non-alcoholic steatohepatitis in HIV mono-infection

Use of non-invasive methods for diagnosis of non-alcoholic steatohepatitis (NASH) in HIV patients and therapeutic use of vitamin E

Reporting

Treatment & Management

CTN 283: the I-Score Study

The development and validation of a patient-reported measure of antiretroviral therapy’s interference with life: a clinical patient-management tool for healthcare providers

Completed

Reporting

Treatment & Management

CTNPT 025: ProSPAR

Progesterone Supplementation for HIV-positive Pregnant Women on Anti-Retrovirals

Completed

Cure & Immunotherapies

CTN 239: Phase II study of AGS-004 an immunotherapeutic agent in combination with ART followed by ART interruption

A phase II study testing the activity and safety of AGS-004 as an immunotherapeutic in successfully ART-treated subjects infected with HIV-1 in combination with ART followed by ART interruption: Trial results

Completed

Prevention & Testing

CTN 268: ANRS IPERGAY trial

On Demand Antiretroviral Pre-exposure Prophylaxis for HIV Infection in Men Who Have Sex With Men

Careers

Interested in joining our team? Here are the current career opportunities with the CTN+ and our collaborators. For Fellowship opportunities, please visit our Postdoctoral Fellowship program page.

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