Treatment & Management

CTN 190: Strategies for management of ART (The SMART Study)

A Comparison of Two Ways to Manage Anti-HIV Treatment

CTN 167: Options with antiretrovirals (OPTIMA)

A tri-national (Canada, UK, USA) randomized, controlled trial to determine the optimal management of patients with HIV infection for whom first and second-line highly active antiretroviral therapy has failed

Completed

Treatment & Management

CTN 151: Multiple Drug Rescue Therapy

A Pilot Study Comparing Two Modalities of Multiple Drug Rescue Therapy (MDRT) among Pre-Treated, HIV-1 Infected Individuals – Full versus Sensitivity-Based MDRT Protocol: Trial results

Completed

Treatment & Management

CTNPT 001: Fracture case-control study in HIV

A case-control study of novel bone imaging techniques and plasma markers in HIV-infected persons with or without fragility fractures

Completed

Treatment & Management

CTNPT 005: Measuring cognition in HIV

Measuring cognitive decline in patients at high risk for developing HIV-related neurocognitive dysfunction

Completed

Treatment & Management

CTN 277: CARMA endo study

Endocrinopathy u0026 cellular aging in women and girls enrolled in the CARMA cohort

Completed

Treatment & Management

CTN 289: E/C/F/TAF switch with ledipasivir-sofosbuvir therapy

Evaluation of E/C/F/TAF switch followed by ledipasivir-sofosbuvir antiviral HCV therapy in HIV-HCV co-infection

Ongoing

Treatment & Management

CTN 293: REPRIEVE trial

Randomized Trial to Prevent Vascular Events in HIV REPRIEVE is the first large-scale randomized clinical research trial to test a strategy for heart disease prevention among people living with HIV. Specifically, REPRIEVE will test whether a daily dose of a statin (pitavastatin) reduces the risk of heart disease among people living with HIV.

Reporting

Treatment & Management