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Our Resource Library is a place to share documents, videos, and training resources about HIV and STBBI research and related topics.
Clinical trials play a pivotal role in advancing medical research and shaping the future of healthcare by evaluating the safety and efficacy of new treatments andinterventions. However, ensuring diverse participation in these trials is essential to truly understand how treatments work across different populations. By includingindividuals from diverse backgrounds, including various racial, ethnic, socioeconomic, and…
In this recording of a talk presented at the 2025 CTN+ Spring Meetings, Dr. Lawrence Mbuagbaw describes the extent and impact of inequalities in health research, potential solutions and frameworks, and practical guidance to achieve health equity.
This document aims to improve research quality and coordination to identify and propose best practices and other measures to strengthen the global clinical trial ecosystem and to review existing guidance and develop new guidance as needed on best practices for clinical trials.
This How-to Guide has been developed for anyone who needs to be involved in the implementation of Patient Engagement in the design of a clinical trial protocol.
Recommendations are provided for a minimum set of items that should be addressed and included in SAPs for clinical trials. Trial registration, protocols, and statistical analysis plans are critically important in ensuring appropriate reporting of clinical trials.
Adaptive trial design has been proposed as a means to increase the efficiency of randomized clinical trials, potentially benefiting trial participants and future patients while reducing costs and enhancing the likelihood of finding a true benefit, if one exists, of the therapy being studied.
The objective of the study was to outline key considerations for general clinical readers when critically evaluating publications on platform trials and for researchers when designing these types of clinical trials.
In this review, using a series of examples derived from equivalence and non-inferiority/superiority RCTs, we describe the main differences and methodological aspects among these three different types of RCTs
The CTN+ supports clinical trials, implementation science projects, and non-interventional research of the highest scientific and ethical standards.
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Our researchers and trainees have produced hundreds of peer-reviewed publications in a wide range of HIV- and STBBI-related areas.