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Resources
Our Resource Library is a place to share documents, videos, and training resources about HIV and STBBI research and related topics.
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CTN+
In this recording of a talk presented at the 2025 CTN+ Spring Meetings, Dr. Lawrence Mbuagbaw describes the extent and impact of inequalities in health research, potential solutions and frameworks, and practical guidance to achieve health equity.
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WHO
This document aims to improve research quality and coordination to identify and propose best practices and other measures to strengthen the global clinical trial ecosystem and to review existing guidance and develop new guidance as needed on best practices for clinical trials.
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JAMA
Recommendations are provided for a minimum set of items that should be addressed and included in SAPs for clinical trials. Trial registration, protocols, and statistical analysis plans are critically important in ensuring appropriate reporting of clinical trials.
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NEJM
Adaptive trial design has been proposed as a means to increase the efficiency of randomized clinical trials, potentially benefiting trial participants and future patients while reducing costs and enhancing the likelihood of finding a true benefit, if one exists, of the therapy being studied.
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J Clin Epidemiol
The objective of the study was to outline key considerations for general clinical readers when critically evaluating publications on platform trials and for researchers when designing these types of clinical trials.
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Intern Emerg Med
In this review, using a series of examples derived from equivalence and non-inferiority/superiority RCTs, we describe the main differences and methodological aspects among these three different types of RCTs
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J Am Coll Cardiol
This paper is a practical guide to the essentials of statistical analysis and reporting of randomized clinical trials, include statistical controversies in reporting and interpretation, the fundamentals of trial design, and statistical challenges in the design and monitoring.
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Trials
Findings from pragmatic trials may be used in KT to provide patients, healthcare providers and policymakers with information to optimize decisions based on how a given strategy or intervention performs under the real world conditions. However, pragmatic trials have been criticized for a number of problems.
Studies
The CTN+ supports clinical trials, implementation science projects, and non-interventional research of the highest scientific and ethical standards.
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Publications
Our researchers and trainees have produced hundreds of peer-reviewed publications in a wide range of HIV- and STBBI-related areas.